Domb Research GroupHebrew University of Jerusalem
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Domb Research GroupHebrew University of Jerusalem

The Domb Research Group at the Hebrew University of Jerusalem advances medicinal chemistry, pharmaceutical sciences, polymer chemistry, and controlled drug delivery — translating molecular insight into therapeutic impact.

  • Institute for Drug Research
    School of Pharmacy, Faculty of Medicine
    Hebrew University of Jerusalem
    Ein Kerem Campus
    Jerusalem 9112102, Israel
  • avid@ekmd.huji.ac.il
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CHn · Drug Delivery · Polymers · Medicinal Chemistry

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publicationSeptember 24, 2026

Congratulations to Matilda and Muhammad on their new publication in ACS journal of agricultural and food chemistry (JAFC)!

Medicinal chemistry

Schematic of naringin phenolate salt synthesis, solubility, and cell proliferation

This study explores naringin phenolate salts as potential bioactive compounds for more cost-effective cultivated meat production. Naringin was converted into phenolate salts to improve its aqueous solubility and enable evaluation under cell-culture conditions. The salts were chemically characterized and investigated for their biological activity under different growth-factor conditions. The findings support phenolate salt formation as a promising strategy for improving the solubility and functional potential of natural polyphenols, with potential applications in developing more economical cultivated-meat culture media.