Domb Research GroupHebrew University of Jerusalem
  • Home
  • About
  • Research
  • Publications
  • Team
  • Gallery
  • News
Get in Touch
Domb Research GroupHebrew University of Jerusalem

The Domb Research Group at the Hebrew University of Jerusalem advances medicinal chemistry, pharmaceutical sciences, polymer chemistry, and controlled drug delivery — translating molecular insight into therapeutic impact.

  • Institute for Drug Research
    School of Pharmacy, Faculty of Medicine
    Hebrew University of Jerusalem
    Ein Kerem Campus
    Jerusalem 9112102, Israel
  • avid@ekmd.huji.ac.il
  • Browse research publications

Research

  • Programmes
  • Publications

Laboratory

  • About
  • Team
  • News
  • Gallery

University

  • Contact
  • Hebrew University
  • School of Pharmacy

© 2026 Domb Research Group · Hebrew University of Jerusalem

CHn · Drug Delivery · Polymers · Medicinal Chemistry

The People

Chemists, pharmacists,
scientists

A multidisciplinary team of faculty, postdoctoral scientists, doctoral candidates, and masters researchers — each contributing distinct expertise across chemistry, formulation, and pharmaceutical science.

Principal Investigator
Portrait of Prof. Avi Domb

Prof. Avi Domb

Principal Investigator

avid@ekmd.huji.ac.il

Prof. Avi Domb is a Professor of Medicinal Chemistry and Biopolymers at the School of Pharmacy within the Faculty of Medicine at The Hebrew University of Jerusalem, where he holds the Lionel Jacobson Chair in Medicinal Chemistry. His academic background spans multiple disciplines, having earned a B.Sc. in Chemistry and Physics, a M.Sc. and Ph.D. in Organic Chemistry from Bar-Ilan University, along with a B.Pharm. in Pharmacy and an LL.B. in Law from The Hebrew University of Jerusalem. He completed postdoctoral research fellowships at Syntex Research (Palo Alto), Harvard Medical School, and MIT under the mentorship of Prof. Judah Folkman and Prof. Robert Langer — a formative period that established his pioneering work on biodegradable polymers and controlled drug delivery systems. Prior to joining the Hebrew University faculty in 1991, Prof. Domb served as Director of Biomaterial R&D at Nova Pharmaceutical Corporation (Baltimore, USA). Over the course of his career, he has held key leadership positions in academia, public service, and government:

* Head of the Division of Identification and Forensic Sciences in the Israel Police, serving with the rank of Brigadier General (2007–2012).

* President of the Azrieli College of Engineering Jerusalem (2014–2016).

* Head of the School of Pharmacy at The Hebrew University of Jerusalem (2018–2021).

* Chief Scientist of the Israeli Ministry of Innovation, Science and Technology (2021–2025).

Prof. Domb has authored or co-authored over 570 scientific publications, holds dozens of issued patents, and has co-founded several biotechnology spinoff companies. His multidisciplinary laboratory focuses on biodegradable polymers, target-specific drug delivery systems, nanomedicine, gene therapy, biomaterials for tissue engineering, forensic science methodologies, and sustainable chemical technologies — actively translating fundamental chemistry from the benchtop into clinical trials and commercialized pharmaceutical products.

Research focus
Drug DeliveryNanotechnologyTissue EngineeringForensic ScienceGene DeliveryBiodegradable Polymers
Research Members

Postdocs, doctoral and masters researchers

Postdoctoral Researchers1
Dr. Awanish Kumar

Dr. Awanish Kumar

Postdoc

Dr. Awanish is expert in the end-to-end development of sophisticated drug delivery systems for small molecules and biomolecules. He did his PhD from University of Delhi, India and later moved to MIT, USA as a Postdoctoral Research Associate. Currently, he is a Senior Postdoctoral Fellow in Prof. Avi Domb research group. Overall, he has 45 publications in peer-reviewed Journals.

Doctoral Researchers2
Muhammad Abdel-haq

Muhammad Abdel-haq

Ph.D. Candidate · Lab Manager

Muhammad research focuses in the formulation, optimization, and scale-up of diverse delivery systems — including polymer-based and particulate systems, diagnostic markers, SNEDDS, and water enrichment platforms. Working at the intersection of academic research and commercial application, he oversees multiple simultaneous projects and leads instrument operation, cross-functional team training, and laboratory resource management.

Formulation & scale-upPolymer delivery systemsDiagnostic markersSNEDDS
Matilda Dirawy

Matilda Dirawy

Ph.D. Student · Medicinal Chemistry

Matilda is a Ph.D. student in Medicinal Chemistry with a background in pharmaceutical sciences (B.Sc. Pharm.). Her research focuses on the synthesis of polyphenolate salts to improve the solubility and bioavailability of bioactive compounds.

Medicinal chemistryPolyphenolate saltsSolubility & bioavailabilityPharmaceutical sciences
matilda.dirawy@mail.huji.ac.il
Masters Researchers2
Marah Abo Mokh

Marah Abo Mokh

M.Sc. student , B.Sc. Pharm

Marah research focuses on the preparation and characterization of biodegradable breast markers for mammography. She develops biopsy marker clips in different shapes by incorporating contrast agents into a biodegradable polymer matrix to improve visualization of the tumor site during clinical follow-up, and engineers hydrophilic coatings to further enhance imaging performance.

Biodegradable polymersBreast markersMammography imagingLipiodol
Saleem Dabbah

Saleem Dabbah

M.Sc. Student · Biomedical Sciences

Saleem holds a B.Sc. in Biomedical Sciences and is pursuing his M.Sc. in the Domb Research Group, contributing to the group's translational drug delivery and biomaterials research.

Biomedical sciencesDrug deliveryBiomaterials
Research Scientists1
Ezz-Aldeen Salaymeh

Ezz-Aldeen Salaymeh

Lab Technician · Pharmaceutical Chemistry

Ezz-Aldeen holds a B.Sc. in Pharmaceutical Chemistry and brings hands-on R&D laboratory experience to the group. He supports formulation development and analytical workflows across projects, with practical expertise in drug release studies, polymer characterization, and microbiology.

Drug release studiesPolymer characterizationMicrobiologyFormulation R&D